Hydrogen Peroxide Activates Endothelial Nitric-oxide Synthase through Coordinated Phosphorylation and Dephosphorylation via a Phosphoinositide 3-Kinase-dependent Signaling Pathway
Open Access
- 1 February 2002
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 277 (8) , 6017-6024
- https://doi.org/10.1074/jbc.m109107200
Abstract
No abstract availableKeywords
This publication has 45 references indexed in Scilit:
- Sphingosine 1-Phosphate and Isoform-specific Activation of Phosphoinositide 3-Kinase βJournal of Biological Chemistry, 2001
- c-Jun N-terminal Kinase Activation by Hydrogen Peroxide in Endothelial Cells Involves Src-dependent Epidermal Growth Factor Receptor TransactivationJournal of Biological Chemistry, 2001
- The Akt kinase signals directly to endothelial nitric oxide synthaseCurrent Biology, 1999
- AMP‐activated protein kinase phosphorylation of endothelial NO synthaseFEBS Letters, 1999
- Role of reactive oxygen species in the signalling cascade of cyclosporine A‐mediated up‐regulation of eNOS in vascular endothelial cellsBritish Journal of Pharmacology, 1998
- Vascular incorporation of alpha-tocopherol prevents endothelial dysfunction due to oxidized LDL by inhibiting protein kinase C stimulation.Journal of Clinical Investigation, 1996
- Requirement for Generation of H 2 O 2 for Platelet-Derived Growth Factor Signal TransductionScience, 1995
- Hypercholesterolemia increases endothelial superoxide anion production.Journal of Clinical Investigation, 1993
- Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells.Journal of Clinical Investigation, 1989
- Paradoxical Vasoconstriction Induced by Acetylcholine in Atherosclerotic Coronary ArteriesNew England Journal of Medicine, 1986