Antibody Responses to Honey-Bee Venom and Monomethoxy-Polyethylene Glycol-Modified Honey-Bee Venom in Mice
- 1 January 1983
- journal article
- research article
- Published by S. Karger AG in International Archives of Allergy and Immunology
- Vol. 71 (3) , 228-232
- https://doi.org/10.1159/000233395
Abstract
Antibody responses of the IgE isotype were raised in mice with honey-bee venom (HBV) administered in alum or by daily injections without adjuvant. The sensitized mice were treated with single injections of HBV modified with monomethoxy-polyethylene glycol. By such treatment with modified but not with natural HBV, suppression of the IgE antibody responses was achieved. The IgG antibody responses, in contrast, were unchanged or enhanced.Keywords
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