Crohn's Colitis Associated with Granulomatous Bone Disease

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Abstract
A Variety of bone and joint manifestations of Crohn's disease have been reported,1 2 3 including ankylosing spondylitis,1 nonspecific synovitis,4 periosteal new-bone formation,5 6 7 and aseptic necrosis.5 One case of granulomatous synovitis has been reported.8 The unusual case of Crohn's disease of the colon reported below was complicated by granulomatous disease of bone.Case ReportA 44-year-old man complained of severe bilateral leg pain progressing, in one month, to the point that he was having difficulty walking. He also complained of mild abdominal distention.Physical examination gave normal results. Urinalysis, complete blood count, glucose, urea nitrogen, cholesterol, uric acid, total protein with albumin-globulin . . .