Effect of Carbon Dioxide on Erythromycin

Abstract
Exposure of erythromycin solutions to CO 2 or air for 18 h resulted in minimal deterioration under both conditions. Saturated disks exposed to the two atmospheres resulted in greater erythromycin deterioration, with slightly more deterioration occurring in the presence of CO 2 . Reduction of activity was greatest when assays were conducted in a CO 2 environment.