The Raf signal transduction cascade as a target for chemotherapeutic intervention in growth factor-responsive tumors
- 1 December 2000
- journal article
- review article
- Published by Elsevier in Pharmacology & Therapeutics
- Vol. 88 (3) , 229-279
- https://doi.org/10.1016/s0163-7258(00)00085-1
Abstract
No abstract availableKeywords
This publication has 461 references indexed in Scilit:
- In VitroInhibition of Ras–Raf Association by Short PeptidesBiochemical and Biophysical Research Communications, 1998
- Geldanamycin, an hsp90/GRP94-binding drug, induces increased transcription of endoplasmic reticulum (ER) chaperones via the ER stress pathwayJournal of Cellular Physiology, 1998
- In VitroTranscriptional Activation of p21 Promoter by p53Biochemical and Biophysical Research Communications, 1997
- Expression patterns and transcript processing of ftt-1 and ftt-2, two C. elegans 14-3-3 homologuesJournal of Molecular Biology, 1997
- Evidence Supporting a Signal Transduction Pathway Leading to the Radiation-Resistant Phenotype in Human Tumor CellsBiochemical and Biophysical Research Communications, 1997
- Raf-1 kinase, epidermal growth factor receptors, and mutant ras proteins in colonic carcinomasDigestive Diseases and Sciences, 1996
- Farnesyltransferase inhibitors and anti-Ras therapyBreast Cancer Research and Treatment, 1996
- Molecular Cloning, Expression Pattern, and Chromosomal Localization of Human CDKN2D/INK4d,an Inhibitor of Cyclin D-Dependent KinasesGenomics, 1995
- Decreased Map Kinase Activity in Human Gastric AdenocarcinomaBiochemical and Biophysical Research Communications, 1995
- Mapping GRB2, a Signal Transduction Gene in the Human and the MouseGenomics, 1994