Paternity after Chemotherapy-Induced Sterility in Hodgkin's Disease

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Abstract
To the Editor: Recent reviews have emphasized the severe azoospermia that occurs in postpubertal male patients after treatment of Hodgkin's disease with MOPP (mechlorethamine, Oncovin [vincristine], prednisone, and procarbazine).1 2 3 4 5 6 Some recovery has been documented, but only in a small percentage of patients and only after at least four years. We would like to report that two men with documented azoospermia after MOPP therapy for Hodgkin's disease have since fathered children.The first patient was 18 years old at the time of diagnosis of Hodgkin's disease. He initially received several courses of nitrogen mustard alone, and three years later (at the . . .