Abstract
Investigations have indicated with a high degree of certainty that carotene may be converted in the liver to vitamin A. This fact makes possible a chemical approach to the problem of the anti-infective action of vitamin A. In the studies about to be reported, the carotinoid pigments of the blood were determined by the method of Connor.1 The pigments determined by this method include carotene and xanthophyll. In order better to understand the results obtained, the vitamin A content of the blood and of the liver in children coming to autopsy and in experimental animals was determined by a modification of the antimony trichloride test of Carr and Price.2 The uncertainty of this method is recognized, but the results appear so consistent and the variations in different conditions are so large, that the method seems sufficient for our purpose. An arbitrary unit is employed. It is equal to

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