Two haplotypes of the P2X7receptor containing the Ala‐348 to Thr polymorphism exhibit a gain‐of‐function effect and enhanced interleukin‐1β secretion

Abstract
The P2X7 receptor is an ATP-gated cation channel expressed in immune cells and plays a role in proinflammatory cytokine release from monocytes and macrophages. This study investigated the coinheritan...
Funding Information
  • National Health and Medical Research Council
  • Cure Cancer Australia Foundation