Differential Expression of High-Affinity Melatonin Receptors (MT1) in Normal and Malignant Human Breast Tissue
Open Access
- 1 September 2002
- journal article
- Published by Oxford University Press (OUP) in American Journal of Clinical Pathology
- Vol. 118 (3) , 451-458
- https://doi.org/10.1309/1t4v-ct1g-ubjp-3ehp
Abstract
Melatonin is a pineal hormone that strongly inhibits the growth of breast cancer cells in vitro and in vivo. We report the first use of immunohistochKeywords
This publication has 25 references indexed in Scilit:
- Disruption of Mitochondrial Respiration by Melatonin in MCF-7 CellsToxicology and Applied Pharmacology, 2001
- Treatment of cancer chemotherapy-induced toxicity with the pineal hormone melatoninSupportive Care in Cancer, 1997
- Melatonin in HumansNew England Journal of Medicine, 1997
- Melatonin receptors step into the light: cloning and classification of subtypesTrends in Pharmacological Sciences, 1996
- Human malignant melanoma cells express high-affinity receptors for melatonin: antiproliferative effects of melatonin and 6-chloromelatoninEuropean Journal of Pharmacology: Molecular Pharmacology, 1993
- Melatonin and 6-sulfatoxymelatonin circadian rhythms in serum and urine of primary prostate cancer patients: Evidence for reduced pineal activity and relevance of urinary determinationsClinica Chimica Acta; International Journal of Clinical Chemistry, 1992
- Stage-dependent depression of melatonin in patients with primary breast cancer. Correlation with prolactin, thyroid stimulating hormone, and steroid receptorsCancer, 1989
- Melatonin Binding SitesJournal of Neurochemistry, 1988
- Melatonin increases oestrogen receptor binding activity of human breast cancer cellsNature, 1983
- Decreased Nocturnal Plasma Melatonin Peak in Patients with Estrogen Receptor Positive Breast CancerScience, 1982