Conversion of the Electrophoretic Pattern of Type IV Hyperlipidaemia to Type III by Intravenous Heparin
- 12 January 1978
- journal article
- research article
- Published by Wiley in Acta Medica Scandinavica
- Vol. 203 (1-6) , 487-490
- https://doi.org/10.1111/j.0954-6820.1978.tb14913.x
Abstract
Heparin was given i.v. to subjects with type IV hyperlipoproteinemia who had only ordinary pre-.beta. lipoproteins and no late pre-.beta. lipoproteins (LP-.beta.) in their very low density lipoproteins (VLDL, d < 1.006) upon agarose gel lipoprotein electrophoresis. Within 15 min the electrophoretic pattern of VLDL changed completely. The normal pre-.beta. lipoproteins disappeared and a discrete LP-.beta. lipoprotein appeared. This new electrophoretic pattern, induced 15 min after heparin, is similar to that diagnostic of type III hyperlipoproteinemia. The LP-.beta. lipoproteins possibly represent an end stage in the catabolism of VLDL.This publication has 21 references indexed in Scilit:
- TYPE-III HYPERLIPOPROTEINÆMIA ("REMNANT REMOVAL DISEASE")The Lancet, 1977
- Comparison of the Behaviour of Very Low Density Lipoproteins of Type III Hyperlipoproteinaemia on Electrophoresis on Paper and on Agarose Gel with a Note on a Late (Slow) Pre-β VLDL LipoproteinScandinavian Journal of Clinical and Laboratory Investigation, 1975
- Quantitative and qualitative serum lipoprotein analysis: Part 1. Studies in healthy men and womenPublished by Elsevier ,1975
- On the metabolic conversion of human plasma very low density lipoprotein to low density lipoproteinBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1973
- Lipoprotein fractionation.Journal of Clinical Pathology, 1973
- Abnormal lipid composition of very low density lipoproteins in diagnosis of broad-beta disease (Type III hyperlipoproteinemia)Metabolism, 1972
- Formation of cholesteryl ester-rich particulate lipid during metabolism of chylomicronsJournal of Clinical Investigation, 1970
- Analysis of change in ultracentrifugal lipoprotein profiles following heparin and ethyl-p-chlorophenoxyiso-butyrate administrationClinica Chimica Acta; International Journal of Clinical Chemistry, 1968
- Studies on the glycerides during the clearing reactionClinica Chimica Acta; International Journal of Clinical Chemistry, 1957
- Blood Lipids and Human AtherosclerosisCirculation, 1951