Alterations in plasma sialyltransferase levels in patients with neoplastic disease
- 1 March 1977
- Vol. 39 (3) , 1129-1134
- https://doi.org/10.1002/1097-0142(197703)39:3<1129::aid-cncr2820390318>3.0.co;2-3
Abstract
Levels of glycoprotein:sialyltransferase activity (EC 2.4.99.1; CMP-acetylneuraminate:D-galactosyl-glycoprotein N-acetylneuraminyl-transferase) were measured in plasma of patients with neoplastic disease, and were found elevated above normal control values in 85% of patients examined. There was a correlation between enzyme levels and course of disease in 46 of 57 patients studied serially during therapy. Plasma sialyltransferase may be a useful marker enzyme for monitoring effectiveness of therapeutic programs for disseminated neoplasms.This publication has 15 references indexed in Scilit:
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