Structural Aspects of Catalytic Activities of Thiazolium Salts in Benzoin Condensation Reaction in Methanol
- 1 March 1980
- journal article
- Published by Oxford University Press (OUP) in Bulletin of the Chemical Society of Japan
- Vol. 53 (3) , 740-744
- https://doi.org/10.1246/bcsj.53.740
Abstract
The rates of benzoin condensation catalyzed by thiazolium salts of varying structures have been determined in methanol containing triethylamine as the base by the method of gas chromatography. The condensation activity was observed not to be linearly correlated with the acidities of 2-position of catalyst thiazolium ring. The dimethylamino substituent was found not to act as an internal base for benzoin condensation, but rather exerted an inhibitory effect. In general, the effects of N-substituent on the rate of benzoin condensation were small. However, a large steric hindrance was observed for 3-methyl-4-menthylthiazolium perchlorate.This publication has 24 references indexed in Scilit:
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