THE EFFECT OF ELECTRICAL ABLATION OF THE NUCLEI HABENULAE, PINEAL BODY AND SUBCOMMISSURAL ORGAN ON ENDOCRINE FUNCTION, WITH SPECIAL REFERENCE TO THYROID FUNCTION1

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Abstract
Although it has been proposed that the habenular nuclei may be a primary center in the control of thyrotropin secretion by the pituitary, in the present study it was found that animals with extensive damage including the habenula, pineal body and subcommissural organ developed thyroid enlargement approximately equal to that of untreated controls when fed propylthiouracil. Thyroidal radioiodine accumulation and testis and adrenal weights were not consistently affected by any of the lesions. There was no persistent change in either serum sodium and potassium concentration or water intake postoperatively.