Platelet-derived Acid Phosphatase Isoenzyme in the Serum in Thrombocythemia
Open Access
- 1 February 1977
- journal article
- research article
- Published by Oxford University Press (OUP) in American Journal of Clinical Pathology
- Vol. 67 (2) , 177-179
- https://doi.org/10.1093/ajcp/67.2.177
Abstract
Tavassoli, Mehdi, and Yelenosky, Robert: Platelet-derived acid phosphatase isoenzyme in the serum in thrombocythemia. Am J Clin Pathol 67: 177–179, 1977. Acid phosphatase is present in platelets and is released during the clotting process. In thrombocythemic conditions, this may increase seruin enzymatic activity. An illustrative case in which the determination of plasma enzymatic activity suggested a platelet origin of elevated serum levels, confirmed by isoenzyme fractionation on disk polyacrylamide gel electrophoresis is presented. It is concluded that in the presence of thrombocytosis a plasma sample is preferable to a serum sample for determination of acid phosphatase activity.Keywords
This publication has 2 references indexed in Scilit:
- An improved acid phosphatase procedureClinica Chimica Acta; International Journal of Clinical Chemistry, 1966
- PLATELETS AS A SOURCE OF SERUM ACID NITROPHENYLPHOSPHATASE*Journal of Clinical Investigation, 1959