Abstract
Wild-type Nostoc calcicola carried out oxygenic photosynthesis extremely sensitive to copper. A Cu2+-resistant mutant (Cu-R1) of the cyanobacterium grew normally at high concentrations of Cu2+. Its ability to grow under such conditions was found to be due to mutational acquisition of an energy-dependent efficient system of Cu2+-efflux, which rendered Cu2+-inhibited oxygenic photosynthesis fully reversible.

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