Synthesis and antiviral activity of acyclovir-5′-(phenyl methoxy alaninyl) phosphate as a possible membrane-soluble nucleotide prodrug

This publication has 16 references indexed in Scilit:

• Mechanism of anti-HIV action of masked alaninyl d4T-MP derivatives.
  Proceedings of the National Academy of Sciences, 1996
• Phosphoramidate derivatives of d4T with improved anti-HIV efficacy retain full activity in thymidine kinase-deficient cells
  Bioorganic & Medicinal Chemistry Letters, 1996
• Aryl Phosphoramidate Derivatives of d4T Have Improved Anti-HIV Efficacy in Tissue Culture and May Act by the Generation of a Novel Intracellular Metabolite
  Journal of Medicinal Chemistry, 1996
• Leading article
  Journal of Antimicrobial Chemotherapy, 1994
• Pharmacokinetics of the acyclovir pro-drug valaciclovir after escalating single-and multiple-dose administration to normal volunteers
  Clinical Pharmacology & Therapeutics, 1993
• Foscarnet Therapy in Five Patients with AIDS and Acyclovir-resistant Varicella-Zoster Virus Infection
  Annals of Internal Medicine, 1991
• Synthesis and anti-HIV activity of some haloalkyl phosphoramidate derivatives of 3′-azido-3′-deoxythymidine (AZT): potent activity of the trichloroethyl methoxyalaninyl compound
  Antiviral Research, 1991
• Acyclovir-Resistant Herpes Simplex Virus Infections in Patients with the Acquired Immunodeficiency Syndrome
  New England Journal of Medicine, 1989
• Nucleic acid related compounds. 37. Convenient and high-yield syntheses of N-[(2-hydroxyethoxy)methyl] heterocycles as "acyclic nucleoside" analogues
  Canadian Journal of Chemistry, 1982
• Selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl)guanine
  Proceedings of the National Academy of Sciences, 1977