Asymptomatic Hyperuricemia: The Case for Conservative Management
- 1 May 1978
- journal article
- research article
- Published by American College of Physicians in Annals of Internal Medicine
- Vol. 88 (5) , 666-670
- https://doi.org/10.7326/0003-4819-88-5-666
Abstract
The management of asymptomatic hyperuricemia is controversial. Reported benefits from treatment include prevention of acute gouty arthritis, chronic tophaceous gout, urolithiasis or gouty nephropathy. A review of experimental and clinical data suggests that the risks of asymptomatic hyperuricemia are small or unknown and the efficiency of long-term treatment in preventing gout or renal disease is unproved. The costs and risks of prolonged drug administration and practical considerations such as patient compliance mitigate against long-term therapy in asymptomatic persons. Some recommendations for an expectant approach to the management of asymptomatic hyperuricemia were offered.This publication has 3 references indexed in Scilit:
- Uric Acid Nephrolithiasis in GoutAnnals of Internal Medicine, 1967
- Diagnostic value of the colchicine therapeutic trialJAMA, 1967
- Predictive Value of a Single Diagnostic Test in Unselected PopulationsNew England Journal of Medicine, 1966