Long-term barbiturate infusion to reduce Intracranial pressure
- 1 June 1983
- journal article
- case report
- Published by Wolters Kluwer Health in Critical Care Medicine
- Vol. 11 (6) , 478-481
- https://doi.org/10.1097/00003246-198306000-00020
Abstract
We report two cases of children, 7 and 14 yr old, in whom prolonged infusion of thiopental sodium (TS) was used to control intracranial hypertension previously unresponsive to conventional therapy. Intracranial hypertension followed removal of a large tumor in 1 case, and trauma in the other. TS was administered at a rate of up to 7 mg/kg . h for 8 days in 1 patient, and up to 12 mg/kg . h for 10 days in the other. Both children regained consciousness and made significant recovery of neurological function. The advantage and the side-effects of the prolonged use of TS for intracranial hypertension are discussed.Keywords
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