Resistance Lowering Effect of Human Respiratory Tract Mucin.

Abstract
Human respiratory tract mucin possesses a resistance-lowering factor similar in activity to that of hog gastric mucin. This effect was shown by intra-bronchial inoculation of rats with pneumococci suspended in saline or the 2 types of mucin. It was also shown by intraperit. inoculation of mice with streptococci suspended in saline, in the 2 types of mucin, or in fractions thereof. Evidence against resistance-lowering properties of mucin depending on the presence of blood group A antigen was obtained by fractionating human respiratory tract mucin and testing the fractions for blood group A antigen and the resistance lowering properties of the fractions.

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