3D image reconstruction algorithms for cryo-electron-microscopy images of virus particles

16 November 2000

proceedings article
Published by SPIE-Intl Soc Optical Eng

Vol. 4123, 231-242
https://doi.org/10.1117/12.409274

Abstract

A statistical model for the object and the complete image formation process in cryo electron microscopy of viruses is presented. Using this model, maximum likelihood reconstructions of the 3D structure of viruses are computed using the expectation maximization algorithm and an example based on Cowpea mosaic virus is provided.

Keywords

3D IMAGE RECONSTRUCTION
ALGORITHMS
ELECTRONS
MICROSCOPY
PARTICLES
VIRUSES
STATISTICAL MODELS
EXPECTATION MAXIMIZATION ALGORITHMS
IMAGE ACQUISITION
ELECTRON MICROSCOPY

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