Purification and properties of the hemagglutinin from Maclura pomifera seeds

Abstract
M. pomifera seeds contain a protein which agglutinates human erythrocytes at concentrations as low as 4 ng/ml. This property is related to its ability to bind with high specificity various .alpha.-D-galactopyranosides. The agglutinin, which was purified by affinity adsorption, exhibits 1 band on immunoelectrophoresis and displays 1 peak during ultracentrifugation, isoelectric focusing and gel permeation chromatography. The active protein has a MW of 40,000-43,000 and contains 2 dissimilar polypeptide chains of 12,000 and 10,000, respectively.

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