Protective effect of polymyxin B sulfate in experimental enterobacterial infection in mice
- 1 September 1979
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Microbiology
- Vol. 25 (9) , 995-998
- https://doi.org/10.1139/m79-153
Abstract
The mouse model of intraperitoneal enterobacterial sepsis was used to evaluate the anti-endotoxic effect of polymyxin B sulfate. Single or multiple therapeutic doses of polymyxin, administered either before or after lethal challenge with Serratia marcescens, produced statistically and clinically significant protective effects.This publication has 8 references indexed in Scilit:
- Characterization of Lipopolysaccharide of Haemophilus influenzaeThe Journal of Infectious Diseases, 1978
- Survey for positive Limulus amoebocyte lysate test in plasma from humans and common research animalsJournal of Clinical Microbiology, 1978
- EFFECT OF METHYLPREDNISOLONE AND POLYMYXIN-B SULFATE ON ENDOTOXIN-INDUCED INHIBITION OF HUMAN NEUTROPHIL CHEMOTAXIS1978
- ENDOTOXIN AND LIVER .3. MODIFICATION OF ACUTE CARBON-TETRACHLORIDE INJURY BY POLYMYXIN-B - ANTI-ENDOTOXIN1978
- Protective effect of polymyxin B sulfate in experimental meningococcal infection in miceCanadian Journal of Microbiology, 1977
- Inhibition of the Biologic Effects of Endotoxin on Neutrophils by Polymyxin B SulfateThe Journal of Infectious Diseases, 1977
- Studies on the Interaction Between Endotoxin and Polymyxin BThe Journal of Infectious Diseases, 1967
- Neutralization of Endotoxin Toxicity in Chick Embryos by AntibioticsJournal of Bacteriology, 1966