Bacteroides fragilis Synthesizes a DNA Invertase Affecting both a Local and a Distant Region
- 1 March 2007
- journal article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 189 (5) , 2119-2124
- https://doi.org/10.1128/jb.01362-06
Abstract
The activity of a fourth conserved tyrosine site-specific recombinase (Tsr) of Bacteroides fragilis was characterized. Its gene, tsr19 , is adjacent to mpi , encoding the global DNA invertase regulating capsular polysaccharide biosynthesis. Unlike the other described Tsrs of B. fragilis , Tsr19 brings about inversion of two DNA regions, one local and one located distantly.Keywords
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