Proteinuria Selectivity Index -Prognostic Value in Lipoid Nephrosis and Related Diseases

1 January 1993

journal article
clinical trial
Published by S. Karger AG in Nephron

Vol. 65 (2) , 185-189
https://doi.org/10.1159/000187472

Abstract

In order to predict the steroid response in lipoid nephrosis (LN), we studied age, sex, proteinuria level, histological features and proteinuria selectivity index (SI; ratio between IgG and transferrin clearances) in 52 LN cases (minimal-change disease: n = 39; focal glomerulosclerosis + IgM nephropathy: n = 13). The multivariate analysis showed that age, sex and proteinuria level were not contributive, whereas histology and SI were. The predictive value of SI was much higher than that of histological type (McFadden’s r²:47% vs. 22%, p

Keywords

MINIMAL-CHANGE DISEASE
FOCAL SEGMENTAL SCLEROSIS
IMMUNOGLOBULIN M NEPHROPATHY
SELECTIVITY INDEX
CAMERON INDEX
STEROID SENSITIVITY

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