The Kelch Proteins Gpb1 and Gpb2 Inhibit Ras Activity via Association with the Yeast RasGAP Neurofibromin Homologs Ira1 and Ira2
Open Access
- 23 June 2006
- journal article
- Published by Elsevier in Molecular Cell
- Vol. 22 (6) , 819-830
- https://doi.org/10.1016/j.molcel.2006.05.011
Abstract
No abstract availableKeywords
Funding Information
- U.S. Department of Defense (W81xwh-04-01-0208)
- Children;s Tumor Foundation (W81xwh-04-01-0208)
This publication has 53 references indexed in Scilit:
- Tfs1p, a Member of the PEBP Family, Inhibits the Ira2p but Not the Ira1p Ras GTPase-Activating Protein in Saccharomyces cerevisiaeEukaryotic Cell, 2004
- Insights into G Protein Structure, Function, and RegulationEndocrine Reviews, 2003
- Recurrent mutations in the NF1 gene are common among neurofibromatosis type 1 patientsJournal of Medical Genetics, 2003
- Krh1p and Krh2p act downstream of the Gpa2p Gα subunit to negatively regulate haploid invasive growthJournal of Cell Science, 2003
- Dynamic regulation of the Ras pathway via proteolysis of the NF1 tumor suppressorGenes & Development, 2003
- Ras membrane targeting is essential for glucose signaling but not for viability in yeast.Proceedings of the National Academy of Sciences, 1995
- The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteinsCell, 1990
- Sequence homology shared by neurofibromatosis type-1 gene and IRA-1 and IRA-2 negative regulators of the RAS cyclic AMP pathwayNature, 1990
- A major segment of the neurofibromatosis type 1 gene: cDNA sequence, genomic structure, and point mutationsPublished by Elsevier ,1990
- Genetic analysis of mammalian GAP expressed in yeastCell, 1989