Multiple defects occur in the guanine nucleotide regulatory protein system in liver plasma membranes of obese (fa/fa) but not lean (Fa/Fa) zucker rats: Loss of functional G1 and abnormal Gs function
- 31 October 1989
- journal article
- Published by Elsevier in Cellular Signalling
- Vol. 1 (1) , 9-22
- https://doi.org/10.1016/0898-6568(89)90016-8
Abstract
No abstract availableKeywords
This publication has 21 references indexed in Scilit:
- Treatment of streptozotocin-diabetic rats with metformin restores the ability of insulin to inhibit adenylate cyclase activity and demonstrates that insulin does not exert this action through the inhibitory guanine nucleotide regulatory protein GiBiochemical Journal, 1988
- G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALSAnnual Review of Biochemistry, 1987
- Abolition of the expression of inhibitory guanine nucleotide regulatory protein Gi activity in diabetesNature, 1987
- Protein kinase C phosphorylates the inhibitory guanine‐nucleotide‐binding regulatory component and apparently suppresses its function in hormonal inhibition of adenylate cyclaseEuropean Journal of Biochemistry, 1985
- Modulation of adenylate cyclase of human platelets by phorbol esterEuropean Journal of Biochemistry, 1985
- Islet-activating protein blocks glucagon desensitization in intact hepatocytesBiochemical Journal, 1984
- Islet-activating protein, pertussis toxin: a probe for functions of the inhibitory guanine nucleotide regulatory component of adenylate cyclaseTrends in Pharmacological Sciences, 1984
- Challenge of hepatocytes by glucagon triggers a rapid modulation of adenylate cyclase activity in isolated membranesBiochemical Journal, 1983
- Is the receptor‐mediated endocytosis of cholera toxin a pre‐requisite for its activation of adenylate cyclase in intact rat hepatocytes?FEBS Letters, 1981
- Cholera toxin mediated activation of adenylate cyclase in intact rat hepatocytesFEBS Letters, 1979