Cerebrovascular Permeability in Acute Arterial Hypertension

Publisher Website
Google Scholar
Abstract
Ligation of the right common carotid artery prevented protein extravasation in the homolateral cerebral hemisphere when a blood pressure increase was induced by bicuclline or amphetamine. In addition to a blood pressure increase these two drugs induce a vasodilatation, which makes the resistance vessels particularly vulnerable to the mechanical stress of high intravascular pressure. The ratio between the mean arterial blood pressure in the femoral artery and the carotid artery distal to the ligation was approximately 0.5; slightly higher after than prior to the pressure increase.