A Multicentre General Practice Study Comparing Pivampicillin (Pondocillin) and Amoxycillin (Amoxil) in Respiratory Tract Infections
- 1 November 1983
- journal article
- research article
- Published by SAGE Publications in Journal of International Medical Research
- Vol. 11 (6) , 370-374
- https://doi.org/10.1177/030006058301100609
Abstract
Seven-day courses of either pivampicillin (Pondocillin) 500 mg twice daily or amoxycillin (Amoxil) 250 mg three times daily were compared in a multicentre general practice study in 463 patients with symptoms of upper or lower respiratory tract infections. Patients were stratified into four diagnostic groups: sinusitis, otitis media, throat infections, and acute bronchitis, and randomly allocated to treatment within these groups. There was an over-all response of 93% in the 227 patients receiving 12-hourly pivampicillin compared with 90% for the 236 patients receiving 8-hourly amoxycillin. Patients suffering from acute bronchitis responded significantly better to pivampicillin (Pondocillin) than to amoxycillin. Side-effects were reported by 15·6% of patients in the amoxycillin group and 14·0% in the pivampicillin group.This publication has 1 reference indexed in Scilit:
- Triple Crossover Study on Absorption and Excretion of Ampicillin, Pivampicillin, and AmoxycillinAntimicrobial Agents and Chemotherapy, 1974