The Change in the Electrical Resistance of the Scala Media Produced by Vasopressin

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Abstract
The electrical resistance of the scaly media (Rm) in the basal turn of the guinea pig was measured during perilymphatic perfusion with vasopressin. As the endocochlear potential (EP) diminished under the influence of vasopressin (0.1 mM), so the Rm increased. The Rm decreased when the EP decreased by vasopressin recovered above the pre-asphyctic level after the termination of temporary asphyxia. The present study demonstrates that the EP decrease produced by vasopressin is associated with the increase in Rm.