Increased amnionic fluid alpha‐fetoprotein due to a holoacardium amorphous twin

Abstract
Amnionic fluid alpha‐fetoprotein measurement was employed as a screening test for neural tube defects in a pregnancy only at risk due to advanced maternal age. The alpha‐fetoprotein concentration was elevated more than 10 standard deviations above the mean and was found to be caused by a holoacardium amorphous twin. A normal female fetus was also present. Various causes of elevated alpha‐fetoprotein concentration in amnionic fluid are discussed.

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