Chiral purity of nucleotides as a necessary condition of complementarity
- 20 October 1986
- journal article
- Published by Wiley in FEBS Letters
- Vol. 207 (1) , 181-183
- https://doi.org/10.1016/0014-5793(86)80036-9
Abstract
This work discusses the question about the role of chiral purity (homochirality) of nucleotides in the formation of complementary replicas. A qualitative answer to this question can be obtained from molecular models constructed to simulate the chiral defect in the polynucleotidic chain. It shows the necessity of homochirality of nucleotides for the complementarity preservation. The necessity of the strong mirror-symmetry breaking in the abiogenic formation of the self-replicating oligonucleotide structures is discussed in the context of prebiological evolutionKeywords
This publication has 2 references indexed in Scilit:
- Rna catalysis and the origin of lifeDiscover Life, 1985
- Chiral selection in poly(C)-directed synthesis of oligo(G)Nature, 1984