Diurnal and seasonal variations in human platelet serotonin in man
- 1 March 1977
- journal article
- conference paper
- Published by Springer Nature in Journal Of Neural Transmission-Parkinsons Disease and Dementia Section
- Vol. 41 (1) , 7-15
- https://doi.org/10.1007/bf01252961
Abstract
Summary Platelet serotonin (5-HT) was found to be an individually constant parameter correlating with the uptake of exogenous 5-HT. A pronounced diurnal pattern of 5-HT, with a minimum in the afternoon and higher values in the morning and evening, was similar to the diurnal variations in plasma free tryptophan. Platelet 5-HT was significantly higher at 8 a.m. than 4 p.m. in spring but no longer in autumn, and was similar in both men and women. It appeared that peripheral diurnal variations in 5-HT were opposite in phase to the central 5-HT rhythm.Keywords
This publication has 17 references indexed in Scilit:
- Sex specific differences in chlorimipramine inhibition of serotonin uptake in human plateletsEuropean Journal of Pharmacology, 1976
- Circadian Variation of Serotonin Levels in Human BloodHormone and Metabolic Research, 1976
- Clinical Relevance of Drugs Affecting Tryptophan TransportAnnual Review of Pharmacology, 1975
- Correlations between circadian changes in serum amino acids or brain tryptophan and the contents of serotonin and 5-hydroxyindoleacetic acid in regions of the rat brainBrain Research, 1975
- Monoamine Oxidase and Free Tryptophan in Human Plasma: Normal Variations and Their Implications for Biochemical Research in Affective DisordersPharmacopsychiatry, 1975
- The daily rhythm of HVA, VMA, (VA) and 5-HIAA in depressionsyndromJournal Of Neural Transmission-Parkinsons Disease and Dementia Section, 1974
- Blood platelets as a model for monoamine-containing neuronesProgress in Neurobiology, 1973
- Daily variations of serotonin metabolism in the rat brainBrain Research, 1972
- THE LEVEL AND DIURNAL RHYTHM OF SERUM SEROTONIN IN MANIC-DEPPESSIVE PATIENTSPsychiatry and Clinical Neurosciences, 1968
- Variations diurnes de la sérotonine libre chez des sujets normauxClinica Chimica Acta; International Journal of Clinical Chemistry, 1968