Simultaneous Determination of Trimethadione and Its Metabolite, Dimethadione, by Gas—Liquid Chromatography
- 1 July 1971
- journal article
- research article
- Published by Oxford University Press (OUP) in Clinical Chemistry
- Vol. 17 (7) , 607-609
- https://doi.org/10.1093/clinchem/17.7.607
Abstract
A simple gas chromatographic procedure is described for the measurement of trimethadione and its major metabolite, dimethadione, in serum. The method, with which compounds can be determined on a single extraction and injection, is reliable and free from interference caused by other drugs, particularly those that the patient is likely to be taking in combination with trimethadione.Keywords
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