Liquid-chromatographic determination of fleroxacin in serum and urine.
Open Access
- 1 November 1988
- journal article
- research article
- Published by Oxford University Press (OUP) in Clinical Chemistry
- Vol. 34 (11) , 2330-2332
- https://doi.org/10.1093/clinchem/34.11.2330
Abstract
This highly sensitive, accurate, and reproducible HPLC method for determining fleroxacin in human serum and urine makes use of a common C18 column, a fluorescence detector, and an internal standard. Serum samples require a simple extraction procedure; urine must be diluted. The method, which we have used extensively for pharmacokinetic assessment of fleroxacin in patients, measures concentrations as low as 5 micrograms/L.This publication has 5 references indexed in Scilit:
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