Absorption of 2′, 3′-Dideoxyinosine from Lower Gastrointestinal Tract in Rats and Kinetic Evidence of Different Absorption Rates in Colon and Rectum
- 1 January 1993
- journal article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 10 (5) , 763-770
- https://doi.org/10.1023/a:1018928320449
Abstract
This study explored the rectal route of administration for 2′,3′-dideoxyinosine (ddI). Rats were given a rectal infusion of nonradiolabeled ddI (200 mg/kg in 0.7 mL saline) over 35 min along with an...Keywords
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