Asymmetric hydrogenation of a carbon–nitrogen double bond in folic acid

1 January 1974

journal article
research article
Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications

No. 10,p. 375-376
https://doi.org/10.1039/c39740000375

Abstract

Asymmetric catalytic reduction of the 5–6 carbon-nitrogen double bond in folic acid has been achived by hydrogenation with an optically active rhodium catalyst.

Keywords

NITROGEN
RHODIUM
ACHIVED
OPTICALLY
ASYMMETRIC HYDROGENATION
DOUBLE
FOLIC
BOND