Class-Conscious TCR?
- 3 December 1999
- journal article
- editorial
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 286 (5446) , 1867-1868
- https://doi.org/10.1126/science.286.5446.1867
Abstract
Resolution of the structure of the T cell receptor (TCR) bound to a complex between an MHC class I molecule and a peptide of processed antigen sheds new light on the molecular complexities of this interaction. Now, in a Perspective, Ian Wilson discusses new work ( Reinherz et al.) that reveals the structure of TCR bound to an MHC class II-peptide complex and compares and contrasts the two classes of structure.Keywords
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