Synthesis of Azaspirodienones via Intramolecular Cyclization of p-Hydroxybenzylacetone Oximes and Their Transformation into Quinolines
- 1 August 1995
- journal article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 24 (8) , 715-716
- https://doi.org/10.1246/cl.1995.715
Abstract
Intramolecular cyclization reaction on the nitrogen atom of oximes of p-hydroxybenzylacetone derivatives proceeds by the treatment with tetrabutylammonium perrhenate and trifluoromethanesulfonic acid in refluxing 1,2-dichloroethane to afford azaspirodienones in good yield. The azaspirodienones are transformed into quinolines via dienone-phenol rearrangement.This publication has 3 references indexed in Scilit:
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- Thermal electrocyclic spirocyclization of p-benzoquinone imines: A novel synthetic route to trifluoromethylated spirodiazacarbocyclesTetrahedron Letters, 1994
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