Weight Loss and Frequency of Feeding

Abstract
THE central role of calories in the production and A maintenance of human obesity is not susceptible to serious challenge. The elucidation of the metabolic anomalies of the hereditary hyperglycemic obese mice by Mayer et al.1 and others,2 however, has led to the consideration of causes of obesity other than simple dietary extravagance.1 , 2 Variation in the amount of exercise has been shown conclusively to be etiologically important in certain cases of obesity.3 The equivalence of isocaloric diets high in fat or carbohydrate in weight maintenance has been questioned.4 , 5 So, too, has the importance of the timing of the consumption of . . .