EFFECT OF DOPAMINE ON PHOSPHATE REABSORPTION IN ISOLATED PERFUSED RABBIT PROXIMAL TUBULES

  • 1 January 1983
    • journal article
    • research article
    • Vol. 9  (3) , 147-150
Abstract
The effect of dopamine (10-6 M) on PO4 reabsorption was studied in isolated and perfused proximal convoluted and straight tubules of the rabbit. In convoluted tubules, fluid reabsorption (Jv), PO4 lumen-to-bath .**GRAPHIC**. and net (net JPO4) fluxes did not change during dopamine exposure. In S3 segments bathed in rabbit serum, Jv diminished significantly during dopamine exposure. JPO4 decreased by 20% (P < 0.005) and net JPO4 decreased by 27% (P < 0.02). The effect of dopamine was reversible upon removal of the drug.

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