Influences of oyster or clam feeding on lipid metabolism in rats.

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Abstract
Rats were fed 1 of 3 diets for 2 wk: (I) a basal diet, (II) containing 0.1% cholate and (III) containing 0.1% cholesterol and 0.1% cholate. Each dietary group was divided into subgroups to which was added 0, 5 or 10% (dry wt) of minced oyster (Callocorchina) or clam (Tapes japonica). The serum and liver cholesterol levels of the rats fed the basal diet were reduced by feeding oyster or clam. The serum and liver triglyceride levels of all dietary groups were lowered markedly by feeding oyster or clam. The activities of glucose-6-phosphate dehydrogenase, malic enzyme and acetyl-CoA carboxylase were reduced in the basal groups fed oyster or clam: these effects were observed in 5 and 10% shellfish feeding. These shellfish may be considered hypolipidemic foods.