Treatment of chromoblastomycosis with terbinafine: A report of four cases
- 1 April 2005
- journal article
- case report
- Published by Taylor & Francis in Journal of Dermatological Treatment
- Vol. 16 (2) , 121-124
- https://doi.org/10.1080/09546630510033203
Abstract
This report is about four cases of chromoblastomycosis confirmed by direct examination, histopathology and cultures. The duration of disease infection varied from 5 to 12 years. By culture, Cladosporium carrionii was isolated in two cases and Fonsecaea pedrosoi in the other two cases. Terbinafine 0.25 g twice daily for 1 month and 0.25 g once daily for maintenance therapy were given to three patients. Terbinafine 0.25 g once daily was given to one patient. After 4-8 months of therapy, all cases were cured without relapse when followed up for 6 months. The total dosage of terbinafine was 37.5-60 g. No relevant side effects showed during treatment.Keywords
This publication has 7 references indexed in Scilit:
- Fonsecaea pedrosoi cerebral phaeohyphomycosis ("chromoblastomycosis"): first human culture-proven case reported in BrazilRevista do Instituto de Medicina Tropical de São Paulo, 2003
- Subcutaneous mycosesInfectious Disease Clinics of North America, 2003
- Chromoblastomycosis: A review of 100 cases in the state of Rio Grande do Sul, BrazilJournal of the American Academy of Dermatology, 2001
- A case of chromomycosis treated by a combination of cryotherapy, shaving, oral 5-fluorocytosine, and oral amphotericin B.The American Journal of Tropical Medicine and Hygiene, 2000
- Terbinafine: broad new spectrum of indications in several subcutaneous and systemic and parasitic diseasesMycoses, 1999
- Therapeutic potential of terbinafine in subcutaneous and systemic mycosesBritish Journal of Dermatology, 1999
- Treatment of chromoblastomycosisJournal of the American Academy of Dermatology, 1991