SYNERGISTIC DELETERIOUS EFFECTS OF NITROUS-OXIDE EXPOSURE AND VITAMIN-B12 DEFICIENCY

  • 1 January 1985
    • journal article
    • research article
    • Vol. 105  (4) , 428-431
Abstract
Rats raised on a vitamin B12-deficient or -sufficient diet were either exposed or not exposed to nitrous oxide for 3 h before sacrifice. Bone marrow cells were assayed for thymidylate synthetase activity by the deoxyuridine suppression test. A synergistic interaction between vitamin B12 deficiency and nitrous oxide exposure was observed.

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