Nodal inhomogeneity mapping by localized excitation—the “NIMBLE” shimming technique for high‐resolution in Vivo NMR spectroscopy

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Abstract
A method (NIMBLE) for obtaining optimum Bo field homogeneity at voxels located away from the magnet isocenter for use in volume‐selected NMR spectroscopy is described. Voxels may be shimmed using only first‐order X, Y, and Z shims to produce three‐dimensional shim current maps, thus avoiding shim coupling problems. NIMBLE shimming prior to volume selection ensures optimum spectral resolution and improves the efficiency and accuracy of the volume‐selection experiment. The benefits of the technique are illustrated by a high‐resolution volume‐selected spectrum of human tibia marrow. © 1988 Academic Press, Inc.