POPULATION SIZES OF GRANULOCYTE-MACROPHAGE AND MONOCYTE-MACROPHAGE COLONY-FORMING CELLS IN SL-SLD

  • 1 January 1978
    • journal article
    • research article
    • Vol. 6  (8) , 673-678
Abstract
The sizes of granulocyte-macrophage (CFU-c) and monocyte-macrophage (CFC) progenitor cell populations were measured and compared in Sl/Sld and +/+ mice. In the marrow, the CFU-c and CFC population sizes were 40% and 67%, respectively, of the +/+ marrow CFU-c and CFC population sizes. There was no difference in the size of these 2-cell populations in the spleens or thymi of Sl/Sld mice as compared with +/+ mice. The marrow CFC population was heterogeneous by velocity sedimentation. One of the marrow CFC subpopulations was characterized by a velocity sedimentation value of 5.05 mm/h while the other has a value of 6.30 mm/h.