Circular Asymmetrical Flow Field-Flow Fractionation for the Semipreparative Separation of Particles
- 4 October 2003
- journal article
- Published by American Chemical Society (ACS) in Analytical Chemistry
- Vol. 75 (22) , 6105-6108
- https://doi.org/10.1021/ac034394z
Abstract
A new technique for the separation and characterization of particles and polymers based on asymmetrical flow field-flow fractionation was developed. The new circular asymmetrical flow field-flow fractionation instrument (CAFFFE) resembles a quasi-parallel arrangement of 12 individual flow channels. As compared to the classical asymmetrical flow field-flow fractionation (AF-FFF), which can be used so far only for analytical separation and characterization of particles and polymers, the CAFFFE allows the introduction of higher amounts of sample into the channel in a single run so that semipreparative to preparative separation becomes possible. This was demonstrated by the separation of polymer latex standards.Keywords
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