Contact-Dependent Inhibition of Growth in Escherichia coli
Top Cited Papers
- 19 August 2005
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 309 (5738) , 1245-1248
- https://doi.org/10.1126/science.1115109
Abstract
Bacteria have developed mechanisms to communicate and compete with each other for limited environmental resources. We found that certain Escherichia coli, including uropathogenic strains, contained a bacterial growth-inhibition system that uses direct cell-to-cell contact. Inhibition was conditional, dependent upon the growth state of the inhibitory cell and the pili expression state of the target cell. Both a large cell-surface protein designated Contact-dependent inhibitor A (CdiA) and two-partner secretion family member CdiB were required for growth inhibition. The CdiAB system may function to regulate the growth of specific cells within a differentiated bacterial population.Keywords
This publication has 16 references indexed in Scilit:
- Bacterial social engagementsTrends in Cell Biology, 2004
- Peptide signaling in Staphylococcus aureus and other Gram-positive bacteriaPeptides, 2004
- Differentiation and developmental pathways of uropathogenicEscherichia coliin urinary tract pathogenesisProceedings of the National Academy of Sciences, 2004
- Extensive mosaic structure revealed by the complete genome sequence of uropathogenic Escherichia coliProceedings of the National Academy of Sciences, 2002
- Genetic Structure and Distribution of Four Pathogenicity Islands (PAI I 536 to PAI IV 536 ) of Uropathogenic Escherichia coli Strain 536Infection and Immunity, 2002
- Cell behavior in traveling wave patterns of myxobacteriaProceedings of the National Academy of Sciences, 2001
- The regulation of pap and type 1 fimbriation in escherichia colaPublished by Elsevier ,2001
- LIVE/DEAD® BacLight™: application of a new rapid staining method for direct enumeration of viable and total bacteria in drinking waterPublished by Elsevier ,1999
- Complete genetic organization and functional aspects of the Escherichia coli S fimbrial adhesin determinant: nucleotide sequence of the genes sfa B, C, D, E, FMicrobial Pathogenesis, 1990
- The frequency of expression of pyelonephritis‐associated pili is under regulatory controlMolecular Microbiology, 1987