Permeability of Normal and Artificially Constructed Canine Urinary Bladders to I131, Na22 and P32

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Abstract
A method was described for the investigation of ion transportation through the mucosa of normal and artificially constructed urinary bladders in dogs using radioactive elements. Animals were anesthesized with intravenous sodium nembutal and catheterized. I131, Na22, and P32, respectively, were instilled into the lumen of the bladder. Blood samples were drawn from the peripheral veins and assayed for radioactivity with a Geiger-Mueller counter. Differences in ion transportation patterns between ileal mucous membrane lined grafts and reversed seromuscular graft and normal controls were demonstrated.

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