Different linkage disequilibria of HLA‐B27 subtypes and HLA‐C locus alleles
- 31 July 1988
- journal article
- research article
- Published by Wiley in Tissue Antigens
- Vol. 32 (2) , 74-77
- https://doi.org/10.1111/j.1399-0039.1988.tb01640.x
Abstract
Subtypes of HLA-B27 have been identified by cellular, serological and biochemical techniques. Comparison of the various B27 subtype designations showed the existence of seven B27 subtypes. The new WHO nomenclature (1987) of the B27 subtypes is included. We further report on different linkage disequilibria (ld) of the B27 subtypes. In Caucasoids, the prevalent subtype B27.5 is in ld with Cwl and Cw2, whereas B27.2 is linked only with Cw2. In Orientals, the most frequent subtypes B27.4 and B27.6 usually occur with Cw3 or Cw blank; B27.5 mostly occurs with Cw2, and B27.2 is almost absent.This publication has 26 references indexed in Scilit:
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