Absence of Specific Binding of Several Putative Neuro-Transmitters to Human Fibroblasts
- 1 January 1983
- journal article
- research article
- Published by Taylor & Francis in Journal of Receptor Research
- Vol. 3 (3) , 409-421
- https://doi.org/10.3109/10799898309041849
Abstract
Fibroblasts were examined for specific binding sites of ten putative neurotransmitters to determine whether this tissue could be used in receptor studies of neurologic and psychiatric disorders. Stereospecific saturable binding was not found for any of the ligands: arginine vasopressin, neurotensin, somatostatin, angiotensin II, thyrotropin-releasing hormone (TRH), α-bungarotoxin, LSD, dihydromorphine, muscimol and spiperone.This publication has 15 references indexed in Scilit:
- High affinity binding sites for a somatostatin-28 analog in rat brainLife Sciences, 1981
- Monoamine oxidase type a in fibroblasts from patients with bipolar depressive illnessPsychiatry Research, 1980
- Binding Sites for Thyrotropin-Releasing Hormone in Sheep Nucleus Accumbens Resemble Pituitary Receptors*Endocrinology, 1980
- Localization of α-bungarotoxin binding sites to the goldfish retinotectal projectionBrain Research, 1980
- Altered nerve growth factor in fibroblasts from patients with familial dysautonomia.Proceedings of the National Academy of Sciences, 1980
- FLUORESCENCE SPECTROSCOPY ON HUNTINGTON'S FIBROBLASTSJournal of Neurochemistry, 1979
- MONOAMINE OXIDASE ACTIVITY IN NORMAL and LESCH‐NYHAN FIBROBLASTSJournal of Neurochemistry, 1978
- Neurotensin: specific binding to synaptic membranes from rat brain.Proceedings of the National Academy of Sciences, 1977
- Distribution of angiotensin II receptors in rat brainBrain Research, 1977
- Specific Binding of [3H]Lysine-Vasopressin to Pig Kidney Plasma MembranesPublished by Elsevier ,1973